Clinical Research Coordinator
Job Summary The general purpose of the position is to help manage and execute all clinical and translational research studies for the Principal Investigators. Currently, the supervising Principal Investigator has two multicenter studies, where UCSF is both the coordinating center and a clinical site, the other PIs have several inter-related projects that operate within the supervising PI's UCSF cohort or with UCSF as a clinical site. In addition, the supervising Principal Investigator has two ongoing studies based in Kampala, Uganda where members of his San Francisco research team help coordinate aspects of this study.
More specifically, the main responsibility of the person in this role is to screen, enroll, and conduct study visits with patients; and to collect, process, store, and ship respiratory (i.e., bronchoscopy with bronchoalveolar lavage, BAL), blood, and other bodiy fluid specimens from HIV-infected and HIV-uninfected subjects in San Francisco that will be used for a wide-range of molecular- and cell-based laboratory assays, including 16S rRNA microarrays and Illumina DNA and RNA sequencing, telomere length and telomerase activity assays, polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA) assays, and unbiased next generation sequencing (NGS) assays. The person will collect and prepare - using sterile laboratory techniques - bronchoscopy with BAL fluid, bronchoscopically-brushed endobronchial cells, and blood (whole blood, serum, plasma, and peripheral blood mononuclear cells (PBMCs)), and bodily fluids (semen abd saliva) for molecular- and cell-based laboratory assays; inventory and store these specimens; arrange proper specimen transport (e.g., on dry ice) to collaborating investigators and staff; oversee the incoming data interpretation from samples and ensure that it is utilized correctly for analysis and publications; organize, manage and update specimen transfer inventories; and ensure the integrity and security of samples.
Additionally, this person will be responsible for pulmonary function testing including spirometry, for which they will receive the appropriate laboratory training. This involves a minimum of three flow-volume loops per subject, both before and after bronchodilator administration (puffs of albuterol). If any concerns or abnormal results are discovered, the person will be responsible for notifying the subject and their primary care physician.
This person will also oversee and receive the shipments of biological specimens from the supervising Principal Investigator's research site in Kampala, Uganda. This person will purchase all study-related supplies for San Francisco and Uganda and will oversee and assist in the cleaning, organizing, and restocking of an office and a Biosafety Level II (BSL2) laboratory. As such, an educational degree in science, theoretical and technical understanding of the laboratory assays, and prior laboratory experience handling infectious (e.g., HIV+ and TB+) specimens are strongly recommended for this position.
The person in this position will work with representatives from the National Institutes of Health, as well as principal investigators, laboratory collaborators, and study personnel from collaborating sites. This person will act as an intermediary between ZSFG and UCSF clinical and research staff to manage all aspects of the Principal Investigators' research studies, which include, but are not limited to all ZSFG, UCSF IRB, and BUA study applications and the day-to-day conduct of study protocols. This person will oversee and assist in the development, execution and, if required, modification and revision of study protocols and laboratory procedures. As such, an in-depth understanding of the laboratory assays being performed and the knowledge and ability to implement the proper biosafety measures are required.
The incumbent will work at an independent level to assist the Principal Investigator with implementing study protocols, study coordination, data/specimen collection, data management, and quality assurance. Specimen collection will include oversight of processing and shipping of study samples and, in cases where this person is a certified phlebotomist, performing blood draws.
This person will also assist the Principal Investigators in the selection and hiring of new laboratory members. The person in this position will be responsible for training all new laboratory members, which include fellows, residents, study coordinators, laboratory assistants, and volunteers or students in all aspects of clinical and translational research.
The person in this position may also be required to execute any and all tasks related to the Principal Investigators' various studies, which include, but are not limited to the screening, recruiting, and enrolling of subjects and the collecting of clinical data and data entry. The person in this position will be responsible, in collaboration with the supervising Principal Investigator's statistician, for creating new systems for organizing clinical data and clinical specimens. The person in this position will assist in the auditing of all of research-related expenditures. This person will participate in all conference calls and meetings and lead lab meetings with the various investigators.
The person in this position will assist the Principal Investigators in preparing grant applications.
The person in this position will also be responsible for managing and assisting in the initiation, implementation, and execution all of the Principal Investigators' future research studies.
Lastly, the person in this position will help to assure compliance with all relevant regulatory agencies; oversee study data integrity; implement and maintain periodic quality control procedures; maintain all regulatory documents; report study progress to investigators; participate in any internal and external audits or reviews of study protocols; and perform other duties as assigned. The final salary and offer components are subject to additional approvals based on UC policy. Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement. The salary range for this position is $34.32 - $55.19 (Hourly Rate). To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html Department Description The Division of HIV, Infectious Diseases and Global Medicine at the University of California, San Francisco (UCSF) is an internationally recognized global leader in clinical care, research, and education. With its home-base located at Zuckerberg San Francisco General Hospital and Trauma Center (ZSFG), the Division has been ranked as the top facility in the country for AIDS care since 1983. The Division's work is featured frequently in the media, and it is often visited by numerous international, national, state, and local dignitaries and delegations. The Division consists of approximately 38 faculty members, 14 fellows/postdoctoral scholars and 170 academic and staff employees. It is the largest Division of the Department of Medicine (DOM) at ZSFG, with a total expenditure budget of approximately $52 million dollars. Required Qualifications
- High school graduation and sufficient experience and demonstrated skills to successfully perform the assigned duties and responsibilities.
- Experience working with individuals in a clinical or a clinical research setting (for example, explaining medical tests and procedures to patients, explaining research procedures and risk/benefit to potential research subjects) and knowledge with medical terminology, medical testing, and human subjects research.
- Attention to detail; strong interpersonal skills; excellent, effective verbal and written communication skills to coordinate with subjects, team members, other departments and outside institutions; and the ability to multi-task in a fast-paced environment while working with a diverse subject population.
- Ability to work well independently, complete projects in a timely manner, and prioritize multiple projects to ensure the completion of essential tasks by deadlines and obtain reproducible results. Excellent analytical and problem-solving skills.
- Knowledge of Microsoft Word, Excel, Outlook, and other basic software programs.
- Current certification in Transportation of Dangerous Goods or ability to obtain certification within first six months of hire.
Preferred Qualifications
- College graduate with a Bachelor's degree, majoring in the biological sciences, and with the associated hands-on laboratory experience (for example, Chemistry lab, Organic Chemistry lab, Biology lab, etc.).
- An educational background in science, theoretical and technical understanding of the laboratory assays, and prior laboratory experience handling infectious specimens (for example, specimens from HIV+ persons and persons with tuberculosis, TB) are strongly suggested for this position
- Competency in R/Excel
- Fluency in the usage of Committee of Human Research (CHR) online iMEDris system for submission, renewal, and modification of protocols through this system.
- Experience with processing specimens such as PBMCs or experience with processing specimens using detailed and advanced protocols (i.e.: familiarity with PBMCs or using specimen processing protocols to isolate and cryopreserve PBMCS); Experience with blood-borne pathogen specimen handling.
- Experience working with vulnerable populations of patients in a medical setting.
- Experience with UCSF/ZSFG electronic medical records.
- Experience with developing and maintaining clinical databases using RedCAP and other types of software.
- Experience applying the following regulations and guidelines:
- Good Clinical Practice Guidelines
- Health Information and Accountability Act (HIPAA)
- The Protection of Human Research Subjects
- Regulations for recruitment and consent of research subjects
- Effective Cash Handling Procedures
- Environmental Health and Safety Training
- CDC's Biosafety in Microbiological and Biomedical Laboratories
- Fire Safety Training
- Certified phlebotomy experience or equivalent certification to perform phlebotomy in the State of California
License/Certification
- Upon hiring, the candidate will obtain (and maintain) required training in Laboratory Safety for Researchers, Biosafety Training, Blood-borne Pathogens Training, Carcinogen Training, Formaldehyde Training, Hazardous Waste Management Training, and Safe Shipper Training.
- Current certification in Transportation of Dangerous Goods or ability to obtain certification within first six months of hire
- Certified phlebotomy experience or equivalent certification to perform phlebotomy in the State of California preferred.
About UCSF The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells. Pride Values UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.
In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu
Join us to find a rewarding career contributing to improving healthcare worldwide. Equal Employment Opportunity The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information. Job Code and Payroll Title 009335 CLIN RSCH CRD Job Category Research and Scientific Bargaining Unit University Professional Technical Employees - Research Support Professionals Unit (UPTE-RX) Location San Francisco, CA Campus Zuckerberg San Francisco General (ZSFG) Additional Shift Details Monday-Friday: 8am-5pm |
University of California - San Francisco Campus and Health
Dec 28, 2024