New

Clinical Research Coordinator II, Dr. Sen Lab

Brigham and Women's Hospital
United States, Massachusetts, Boston
181 Longwood Avenue (Show on map)
Dec 26, 2025
The Sen Laboratory at Brigham and Women's Hospital is looking for an applicant to work in a translational research lab that focuses on studies of immune dysregulation in bone marrow and solid organ transplant recipients. The applicant will participate in clinical research coordination, including patient-facing activities in the inpatient and outpatient academic hospital setting and laboratory research related to coding and processing human clinical specimens to characterize how immune and non-immune cells change in response to immune suppression and different infections. Knowledge gained from these studies will guide more individualized approaches to immunosuppression and opportunistic infection management in immunocompromised hosts. The applicant will work independently under the general supervision of the Principal Investigator; perform duties in accordance with established hospital policies and procedures, and conduct a variety of patient-facing and human specimens based studies with established methodologies; participate in the design and modification of clinical/translational research protocols; compose and may present sections of research reports and manuscripts; and perform data analysis using appropriate statistical techniques. The applicant will also coordinate patient-facing research activities and undertakes quality assurance programs and may supervise new clinical research staff. PRINCIPAL DUTIES AND RESPONSIBILITIES: Patient-facing clinical research coordination, including but not limited to using health information systems (i.e. Epic) to identify potential participants for ongoing translational research studies; consent of potential research subjects for human subjects research approved through appropriate and established institutional review board (IRB) approved protocols; coordination of specimen collection for research with medical and allied health professionals within academic hospital settings. Management of human subjects research IRB protocols under the supervision of Principal Investigator. Maintenance of database linking relevant clinical metadata to specimen collections within translational research studies. Processing and logging of clinical human blood (i.e. cryopreservation) and tissues specimens (i.e. flash frozen, OCT embedded, FFPE blocks) from immunocompromised and healthy patients. Organization of systems immunology and spatial transcriptomics studies of clinical specimens under supervision of Principal Investigator. Participates in the design and modification of clinical and translational research protocols. Responsible for the coordination and scheduling of all patient-facing procedures. If entry-level research staff is present, responsible for supervising staff in the lab. Participates in budget and grant development as needed by the Principal Investigator. Records data, summarizes, and analyzes results using basic statistics. Prepares clinical and translational research protocols and reagents as needed. Attends weekly lab meetings and discusses progress of work regularly with supervisor. All other duties as assigned. SKILLS/ABILITIES/COMPETENCIES REQUIRED: Experience and interest in working directly with patients receiving medical care in the inpatient and outpatient clinical settings. Familiarity with Epic healthcare systems. Familiarity with and willingness to learn how to manage and update standard, HIPAA compliant clinical databases (i.e. REDCAP). Interest and comfort in working with human clinical specimens (blood and tissue). Outstanding organizational skills and highly detail oriented. Sound degree of computer literacy with basic programs (i.e. Microsoft Word, Excel, Powerpoint) and reference managers (i.e. Zotero) with willingness to learn Adobe Illustrator. Ability to record and analyze data using Prism and other basic statistics. Outstanding interpersonal and communication skills with the highest level of professionalism. Education Bachelor's Degree Science required Experience Related post-bachelor's degree research experience 1-2 years required The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.